Targeted Delivery
Precise tissue/cell expression via multidimensional targeted delivery.
RNA Engineering
RNA Engineering
Enhanced expression, durability and selectivity.
Robust CMC
Efficient, reliable manufacturing at scale.
Data Science & AI
From early discovery to product development.
Targeted Delivery
• Clinical-stage, proprietary mRNA delivery with high efficiency, safety, and spleen tropism.
• 10,000+ ionizable lipids, including10+ exhibiting robust extrahepatic expression from a preliminary screen using 500 candidate lipids.
• A multidimensional approach combining passive and active targeting and selective expression to overcome delivery bottleneck.
RNA Engineering
• Engineered antigens and sequence elements for higher stability and expression.
• Poly(A) tail engineering for enhanced and selective expression.
• Circular RNA for regualtory factors.
Robust CMC
• End-to-end processes for RNA synthesis, purification, and formulation.
• Established QC and release testing; products validated by the National Institute for Food and Drug Control (NIFDC).
• Scalable processes ready for commercialization.
Data Science & AI
• Antigen prediction, protein design, and sequence optimization, target identification by comprehensive bioinformatic analysis.
• Ionizable lipid & targeted delivery design/optimization.
• Process design/optimization.
• Protected by multiple registered software copyrights.
